GABA is a neurotransmitter that provides a wide variety of nootropic benefits when taken as a dietary supplement.


  • Increases amount of Human Growth Hormone – leads to improved muscle growth, reduces levels of body fat at a quicker rate [3]
  • Treats anxiety and depression [1]
  • Calming effect that can prove helpful with OCD and Insomnia [1]
  • Relieves PMS [2]
  • Improves mood [2]
  • Stabilizes blood pressure and relieves pain [2]

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What Is GABA?

GABA is a neurotransmitter found in the central nervous system.  Since its discovery as such an important part of our central nervous system is has been synthesized and is currently sold as a supplement. It is a popular supplement among body builders that is also purchased for people seeking to improve mood and lower anxiety. Even though there are over 43,000 published papers on PubMed today a very select few focus on GABA’s use as an oral supplement.

GABA Dosage Information

The appropriate dose of GABA depends on factors such as the user’s age, health, and weight. Even though there is no suggested dosage for GABA there are reports of it being successful at certain dosages.

For those people attempting to increase their HGH a dosage between 3 – 18 grams daily has proven successful. [1] For those trying to treat anxiety or fight insomnia a dosage of 500mg to 1000mg is recommended. When taking GABA to help with insomnia it is best to take it right before sleep.

How Does GABA Work?

GABA plays a role in regulating neuron excitability throughout the entire central nervous system. GABA works as an inhibitory neurotransmitter. Other neurotransmitters communicate with synapses in the brain by fitting into certain receptors and “firing” an electrical impulse that is then interpreted by the brain. GABA does the opposite; it fits into certain receptors to block other neurotransmitters from firing off their impulses. This inhibitory neurotransmitter, along with many others, is very important for regulating the brain. Without GABA certain nerves would fire too often. This can lead to anxiety disorders including panic attacks, and seizures. [1]

Safety and Side Effects of GABA

The most common side effects people experience are itching and tingling sensations. Other people have reported an increase in heart-rate and heavy breathing. In rare cases nausea has also been reported. Long-term effects from prolonged use of GABA supplements are not known. There are no known drug interactions.


Below are some of the most commonly asked questions about GABA. If you have a question that’s not on this list, send it to us at [email protected] and we will answer it for you.

Should I Use GABA?

GABA can possibly be helpful for those trying to lose weight and build muscle. One problem with GABA is debate on whether an oral supplement can cross the blood-brain barrier. In theory, if GABA cannot cross this barrier then it would have no effects. Some people have hypothesized that at larger doses some of it can spill over. This is evidenced by the large doses of 3-18 grams that have shown success for weight loss and muscle building.People have also blamed its success in other areas on the placebo effect. Either way, there is no evidence to suggest that GABA improves any cognitive functions so if that is your goal look else-ware. I would also recommend trying other sleep and mood aids before using GABA because others are more proven and studied.

Everyone’s body works differently and the only way to know if GABA will work for you is to try it. If you have not had success with other sleep aid, weight-loss, or muscle building supplements then it can’t hurt to give GABA a try.

What Are Some Notable Studies Performed on GABA?

One study conducted in 2008 by Shenandoah University, VA, aimed to determine is oral administration of GABA had any effect on resting HGH levels. The study used eleven man aged 18-30 years of age. During the experiments the man ingested either a 3 gram dosage of GABA or a placebo. They were then resting or resistance exercise sessions. Blood samples were acquired at 15 minute intervals after ingestion. The results concluded that those who took the GABA supplement had significantly higher levels of HGH when compared to the placebo for resting and resistance sessions. These levels peaked at 400%+ and were seen as low as 50%+.

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Cited Studies

1. Denver Naturopathic Clinic:

2. WebMD:

3. Powers ME, Yarrow JF, McCoy SC, Borst SE (January 2008). “Growth hormone isoform responses to GABA ingestion at rest and after exercise”. Medicine and science in sports and exercise 40 (1): 104–10. doi:10.1249/mss.0b013e318158b518. ISSN 1530-031. PMID 18091016.